What is the most important information I should know about Atopica Cyclosporine: Notify your veterinarian immediately if your pet develops fever (over 103 degrees), painful urination, tiredness, sneezing, coughing, or runny nose.These symptoms could be early signs of dangerous side effects.
What is Atopica: Atopica (cyclosporine modified) is an immunosuppressant available by prescription. Atopica is FDA approved for use in the treatment of atopic dermatitis in dogs at least 6 months of age and at least 4 pounds. Atopica is available in 15 capsule blister packs in strengths of 10mg for dogs 4 to 9 pounds, 25mg for dogs 9.1 to 16 pounds, 50mg for dogs16.1 to 33 pounds and 100mg for dogs 33.1 to 64 lbs. For dogs 64.1 to 79 pounds give a combination of one 100mg capsule and one 50mg capsule as a single dose. For dogs 79.1 to 121 pounds give two 100mg capsules as a single dose. Atopica is given once a day to start until satisfactory improvement is seen, usually 4 to 8 weeks. The medication can then be given every other day until the clinical signs of atopic dermatitis are satisfactorily controlled, then the medication can be given every 3 or 4 days.
What should I discuss with my veterinarian before giving Atopica Cyclosporine: Tell your veterinarian if your pet has liver disease, kidney disease, cancer, high blood pressure, a viral, bacterial or fungal infection, or any other serious or chronic condition. Tell your veterinarian if your pet is pregnant or lactating, and if you plan to breed your pet.
How should this medication be given: Give Atopica Cyclosporine exactly as directed by your veterinarian. If you do not understand these directions, ask your veterinarian or pharmacist to explain them to you. Always give Atopica 1 hour before or 2 hours after a meal. Allow plenty of water for the pet to drink. Do not remove a capsule from the blister pack until required for use. When the capsule is removed from the blister pack there is a characteristic, noticeable smell which is normal. Your veterinarian may want your pet to have regularly scheduled blood tests during treatment to monitor effectiveness and side effects. Store Atopica at room temperature away from moisture and heat.
What happens if I miss giving a dose: Give the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and give the next regularly scheduled dose. Do not give a double dose unless otherwise directed by your veterinarian.
What happens if I overdose the pet: Seek emergency veterinary medical treatment.
What should I avoid while giving Atopica to my pet: The safe use in breeding, pregnant or lactating dogs has not been determined. Do not use Atopica in dogs with known allergy to the medication. The drug should not be used in dogs with kidney disease, stomach ulcers, and certain blood disorders. Prolonged use of Atopica can result in bacterial or fungal infection related to a decreased effect of the immune system.
What are the possible side effects of Atopica Cyclosporine: If any of the following serious side effects occur, stop giving Atopica and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing, swelling of the lips, tongue or face, and hives). Other less serious side effects may occur. Continue giving Atopica and talk to your veterinarian if your pet develops vomiting, soft stools or diarrhea, muscle cramps, muscle weakness, loss of appetite, and change of hair coat. Other side effects may occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.
What other drugs will affect Atopica Cyclosporine: There are many drug/drug interactions that occur when taking Atopica. Tell your veterinarian what medications your pet is currently using and any new products, including herbal remedies you may start to give. Drug/drug interactions could cause a decrease in effectiveness or an increase in side effects of either Atopica or the other medication being given. Examples of medications that may cause drug/drug interactions are; SMZ-TMP (Bactrim, Septra), gentamicin, etodolac (EtoGesic), piroxicam (Feldene), ketoconazole (Nizoral), cimetidine (Tagamet), ranitidine (Zantac), itraconoazole (Sporanox), methylprednisolone (Medrol), erythromycin, Allopurinol (Zyloprim), metoclopramide (Reglan), prednisOLOne, digoxin (Lanoxin), any type of vaccination.
Where can I get more information: Your pharmacist has additional information about Atopica written for health professionals that you can read.